Bone and soft-tissue cancer in children: New insights into metastasis

Ewing sarcomas are highly aggressive tumours that can develop in bone or soft tissue and mainly affect children and young people. Regulatory proteins play a key role in the spread of metastases by activating specific genetic networks. Some of these key proteins could be used to predict the course of the disease in patients, as shown by a recent study by the Hopp Children’s Tumour Centre Heidelberg (KiTZ), the German Cancer Research Centre (DKFZ) and Ludwig Maximilian University of Munich (LMU). The research project was funded by the Wilhelm Sander Foundation.